OSLI Retina

December 2016

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December 2016 · Vol. 47, No. 12 1087 using primarily hand-held SD-OCT devices, 10-14 the current study attempts to describe the imaging findings in a large cohort of adolescent and adult patients with history of ROP. Here, we report our findings and their functional correlations with vision and discuss their implications for management. PATIENTS AND METHODS The study was approved by the institutional review board/ethics committee, conformed to the requirements of the Health Insurance Portability and Accountability Act of 1996, and followed the tenets of the Declaration of Helsinki. The study is a single-center, retrospective, noncomparative, consecutive case series of patients with history of ROP who were examined at Associated Retinal Consultants between January 2011 and December 2015. Participants were identified by their International Classification of Diseases (ICD) codes. Patients who underwent SD-OCT (Spectralis; Heidelberg Engineering, Heidelberg, Germany) imaging with or without enhanced depth imaging (EDI) were included. Sessions with time-domain OCT (TD-OCT), uninterpretable SD-OCT images, or eyes with no light perception were excluded from the study. The following data were recorded: demographics at the first imaging session; best-corrected visual acu- ity (BCVA) using automated refracting Snellen acuity charts; laser, cryotherapy, and/or surgical treatment history; and total number of imaging sessions. ROP grading was performed according to the Interna- tional Classification of Retinopathy of Prematurity. 15 SD-OCT/EDI images were analyzed for vitreoretinal interface, preretinal, intraretinal, and choroidal ab- normalities. The total number of abnormalities seen on SD-OCT was noted for each eye. Central foveal thickness was measured manually from the internal limiting membrane to the outer border of the retinal pigment epithelium using the caliper function of the TABLE 1 Demographic and Clinical Features of Patients With ROP Undergoing SD-OCT Feature Number (%) Age, Years (n = 112 patients) Mean (median, range) 31.5 (22.5, 8 – 70) Sex Male 50 (45) Female 62 (55) Eye Imaged (n = 186) Right only 18 (10) Left only (13) Both 72 (77) Eyes Excluded (TD-OCT, Prosthesis, NLP Vision) 38 (20) Highest ROP Stage Stages 1 & 2 44 (24) Stage 3 (TW) 80 (43) Stage 4A 43 (23) Stage 4B 12 (6) Stage 5 7 (4) Previous Treatment None 52 (28) Laser 88 (47) Cryotherapy 8 (4) Surgery 38 (21) ROP = retinopathy of prematurity; SD-OCT = spectral-domain optical coherence tomography; SD = standard deviation; TW = treatment warranting; NLP = no light perception; TD-OCT = time-domain OCT

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