OSLI Retina

December 2016

Issue link: http://osliretina.healio.com/i/761988

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1082 Ophthalmic Surgery, Lasers & Imaging Retina | Healio.com/OSLIRetina Practical Retina green dyes may cause allergic reactions. 1,3 OCTA is also faster and cheaper, and hence can be performed more frequently compared to conventional angiograms. Since its introduction, OCTA has been applied to the management of many common retinal conditions. AGE-RELATED MACULAR DEGENERATION In neovascular age-related macular degeneration (AMD), choroidal neovascularization (CNV) lesions are traditionally imaged using fluorescein angiography (FA) and indocyanine green angiography (ICGA). OCTA is useful in detecting the CNV lesion (Figure 1) and monitoring its progress during treatment. In one study, CNV lesions were reported to have been detected in 64.4% of eyes when compared to FA. 4 On OCTA, the CNV lesions are located in the outer retina and choriocapillaris layers (Figure 1B), 5 consistent with the pathophysiology of the disease. In contrast, Figure 1. Age-related macular degeneration. (A) Fluorescein angiogram demonstrating leakage consistent with ocular choroidal neovas- cularization (CNV) superior to the fovea. (B) Optical coherence tomography angiography (OCTA) of the choriocapillaris layer demonstrat- ing CNV. (C) Indocyanine green angiography with the CNV net visible superior to the fovea. (D) OCT illustrating elevation of the retinal pigment epithelium with subretinal fluid and intraretinal cysts.

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