OSLI Retina

December 2020

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732 Ophthalmic Surgery, Lasers & Imaging Retina | Healio.com/OSLIRetina ■ I M A G E S I N O P H T H A L M O L O G Y ■ Coexistent Retinoblastoma and Retinopathy of Prematurity in a Preterm Infant Abhishek Das, MS; Ratnesh Ranjan, MS; Parag K. Shah, DNB A preterm infant with gestational age of 29 weeks and birth weight of 1,300 grams was screened for reti- nopathy of prematurity (ROP) at 2 weeks of age in a tertiary care facility. Fundus examination revealed a demarcation line (stage 1 ROP) with group B retino- blastoma in both eyes along with peripheral avascular retina and shunt vessels during routine ROP screen- ing. B-scan ultrasonography revealed intra-tumoral calcification, which was more evident in the left eye. Findings of magnetic resonance imaging of the brain and orbit corroborated with the diagnosis of bilateral retinoblastoma without any central nervous system involvement. Similar findings have been previously reported by Benz at al., where coexisting lesions were noted at postmenstrual age (PMA) of 36 weeks in a baby born at 24 weeks with a positive family history of retinoblastoma. 1 To the best of our knowledge, we report the earliest presentation, in terms of PMA, of simultaneous bilateral retinoblastoma and ROP. REFERENCE 1. Benz MS, Escalona-Caamaño EM, Murray TG. Simultaneous presen- tation of retinopathy of prematurity and bilateral familial retinoblas- toma in a premature infant. J Pediatr Ophthalmol Strabismus. 2003; 40(2):98-100. PMID: 12691233 [Ophthalmic Surg Lasers Imaging Retina. 2020;51:732.] From the Department of Pediatric Retina & Ocular Oncology, Aravind Eye Hospital, Tamil Nadu, India. Originally submitted September 25, 2020. Revision received October 29, 2020. Accepted for publication November 9, 2020. The authors report no relevant financial disclosures. Address correspondence to Abhishek Das, MS, Department of Pediatric Retina & Ocular Oncology, Aravind Eye Hospital, Avinashi Road, Coimbatore- 641 014, Tamil Nadu, India; email: abdas.78@gmail.com. doi: 10.3928/23258160-20201202-09 Figure 1. (A) The wide field digital imaging (RetCam 3; Natus, Pleasanton, CA,) of right eye revealed a demarcation line (black arrow) with few ischemic areas along with a small tumor, approximately 1 disc diameter (white arrow) supero-temporal to fovea. (B) Widefield imaging of left eye showed early shunting of blood vessels, demarcation line and ischemic areas (black arrows) with a vascularized tumor at macula (white arrow) which is approximately 4 disc diameter in size.

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