OSLI Retina

September 2020

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September 2020 · Vol. 51, No. 9 535 FRAT manifests as isolated torturous small arte- rioles confined to the posterior pole. Patients with fRAT may present with asymptomatic or symptomat- ic intraretinal or preretinal hemorrhages. 1 Situs inver- sus of the optic disc is a distinct congenital condition with dysversion optic disc and the inserted vessels. This anomaly may be complicated with high myopia, tilted optic disc, or optic disc coloboma. 2,3 The asso- ciation between the coexisting situs inversus of the optic disc and fRAT in our patient remains unclear. Sunah et al. described thicker RNFL in the nasal quadrant and smaller cup-to-disc ratio in the eyes with situs inversus of the optic disc compared to the normal eye. 4 The result was consistent with our case. Although several cases and literature of fRAT have been well described, 1,5,6 to our knowledge, this is the first report of fRAT associated with unilateral situs inversus of the optic disc. REFERENCES 1. Sutter FK, Helbig H. Familial retinal arteriolar tortuosity: a review. Surv Ophthalmol. 2003;48(3):245-255. https://doi.org/10.1016/ S0039-6257(03)00029-8 PMID:12745002 2. Rao VA, Sambath T, Madhavaranga MP, Nair N. Optic nerve en- trance coloboma associated with situs inversus. Indian J Ophthalmol. 2002;50(4):328-329. PMID:12532503 3. Dorrell D. The tilted disc. Br J Ophthalmol. 1978;62(1):16-20. https://doi.org/10.1136/bjo.62.1.16 PMID:629907 4. Kang S, Jin S, Roh KH, Hwang YH. Peripapillary retinal nerve fi- ber layer and optic nerve head characteristics in eyes with situs inver- sus of the optic disc. J Glaucoma. 2015;24(4):306-310. https://doi. org/10.1097/IJG.0b013e31829e1ba2 PMID:24048184 5. Bartlett WJ, Price J. Familial retinal arteriolar tortuosity with retinal hemorrhage. Am J Ophthalmol. 1983;95(4):556-558. https://doi. org/10.1016/0002-9394(83)90282-9 PMID:6837703 6. Ding PC, Chen MT. Retinal arteriolar tortuosity with recurrent reti- nal hemorrhages—case report. Kaohsiung J Med Sci. 2000;16(7):380- 382. PMID:11079298

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