OSLI Retina

February 2020

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128 Ophthalmic Surgery, Lasers & Imaging Retina | Healio.com/OSLIRetina News and Notes News and Notes AGTC's Retinitis Pigmentosa Gene Therapy Candidate Shows Positive 6-Month Results An adeno-associated virus-based gene therapy improved visual function in pa- tients with X-linked retinitis pigmentosa (XLRP) 6 months after dosing, Applied Genetic Technologies Corporation announced in a press release. Secondary data from a phase 1/2 clinical trial showed a favorable safety pro- file in all 25 patients treated with the adeno-associated virus-based gene therapy product candidate. Patients treated centrally showed durable improvement in visual function. "These promising results further demonstrate that our XLRP candidate has tremendous potential to provide meaningful benefit to XLRP patients who today have no treatment options," Sue Washer, president and CEO of Applied Genetic Technologies Corporation, said in the release. "The positive results observed to date give us confidence that the data as a whole will support advancement of our XLRP clinical program to a pivotal trial in 2020." Originally published on Healio.com on January 10, 2020. Ophthalmic Surgery, Lasers & Imaging Retina® (ISSN-2325-8160, Canadian BN-12978 0466 RT ) is published 12 times per year by SLACK Incorporated®, and is an official publication of ARVO/ISIE. Publication Office: SLACK Incorporated®, 6900 Grove Road, Thorofare, NJ 08086-9447. Telephone (856) 848-1000. Printed in the USA. Periodicals Class Postage Paid at Deptford, NJ 08096 and at additional mailing offices. Contents copyrighted by SLACK Incorporated®, 2020. All rights reserved. No part of this publication may be reproduced with- out prior written consent of the publisher. All requests to reprint or use material published herein should be directed to the Request Permissions link on every article page at Healio.com/ophthalmology/journals/osli. Subscription rates in the U.S. and possessions: Individuals: One year—print $228, electronic only: $203. Institutional: One year—$719. Residents and fellows: $114 for one year (a letter of certification indicating residency of the subscriber is required). Canada add 5% GST, all other countries add $64 per year. All subscriptions, without exception, will start with the first issue pub- lished after the order is received. Single copies and back issues, when available, are $103. Payment must accompany order. Sub- scription requests should be addressed to the publisher. Change of Address: Notice should be sent to the publisher six weeks in advance of effective date. Include old and new ad- dresses with zip codes. The publisher cannot accept responsibility for undelivered copies. Duplicate copies will not be sent to re- place ones undelivered through failure to notify the publisher of change of address. POSTMASTER: Send Form 3547 to Ophthalmic Surgery, Lasers & Imaging Retina®, SLACK Incorporated®, 6900 Grove Road, Thorofare, NJ 08086-9447. Articles are intended for informational purposes only and should not be used as the basis of patient treatment. All opinions expressed by authors and quoted sources are their own and do not necessarily reflect the opinions of the editors, publisher, or editorial boards of SLACK Incorporated®. The acceptance of advertising in no way implies endorsement by the editors, publisher, or editorial boards of SLACK Incorporated®. See website for print and web advertising policy. Readers with queries about the Journal's policies on error correction, version control, journal of record, ancillary material, or archiving should contact osli@healio.com. The Journal staff have no financial relationships to disclose. Financial disclosures for the Editor and members of the Editorial Board are on file with the editorial office. Indexed in: Medline/PubMed, ProQuest, EMCare, EMBASE, Science Citation Index, Current Contents/Clinical Medicine, BioEn- gineering Abstracts, CAB Abstracts, and SCOPUS. Follow OSLIJournal OSLI Retina SLACK Incorporated 6900 Grove Road Thorofare, NJ 08086-9447 Phone: 856-994-9900 Email: osli@healio.com Healio.com/OSLIRetina Chief Content Officer Joan-Marie Stiglich, ELS EDITORIAL Senior Editorial Director David W. Mullin Executive Editor Cara Dickinson SALES Chief Commercial Officer Matthew J. Holland Group Sales Director, Eye Care Scott Wright Senior Account Manager Kathy Huntley National Account Manager Laura Renna Director, Sales Administration and Support Carolyn Boerner Sales Coordinator, Recruitment Jennifer Carroll Classified/Recruitment Sales KERH Group LLC 855-233-8100 slack@kerhgroup.com Reprints/Eprints Licensing Opportunities: Sheridan Content Solutions scsreprints@sheridan.com DESIGN Creative Director Thomas Cavallaro Production and Circulation Director Cheryl McKeown Production Associate Ryan Davis The Wyanoke Group President Peter N. Slack Chief Operating Officer John C. Carter Chief Financial Officer Darrell Blood Senior Vice President Denise Mealey Chief Technology Officer Linda Baker

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